Well, sort of. While Cee Lo Green's "F*** You" video is about as politically incorrect as you can possibly get, the cleaned-up radio version is wholesome enough for no less than than Gwyneth Paltrow to perform on nothing less than Glee this coming week.
Take a basic Holland-Dozier-Holland-ish four chord circular progression hook, add a youthful acrobatic melody that keys off the driving bass line, a strong R&B beat, and it sounds like something from the summer of '67. As long as you don't, like, actually sing the real lyrics. Think "You Can't Hurry Love" as performed by the Supremes while suffering from Tourettes.